Researchers have developed a hand-held probe that can obtain images of individual photoreceptors in babies' eyes. The technology, based on adaptive optics, will make it easier for doctors and researchers to observe these cells to diagnose eye diseases and make early detection of diseases and traumas related to the brain.
Photoreceptors are specialized neurons that comprise cells that are sensitive to the light of the retina, an extension of the central nervous system located in the back of the eye. The retina sends signals to the brain through the optic nerve, which then processes the visual information. Earlier examinations have revealed that neurodegenerative disorders, like as Alzheimer's, as well as traumatic brain injuries and disorders, such as concussions, can treat the neural structures of the retina.
After studies, professionals commonly work with AOSLO (adaptive optical scanning laser ophthalmoscope), that is a non-invasive device that provides higher resolution as the comparison of magnetic resonance imaging (MRI).
Other researchers are saying that the wavefront sensor can be replaced by an algorithm because previous algorithms have not been fast and active or robust enough to be used in a handheld method.
The algorithm we develop is much faster than the previous techniques and just as accurate. The tool was tested in a clinical trial with some adults and children, where the team demonstrated its ability to capture detailed images of photoreceptors near the fovea: the center of the retina where the photoreceptors are smaller and the vision sharper.
Our new tool is fast and light so that doctors can take it directly to their patients, and the probe allows us to collect images quickly, even if there is movement. These capabilities allow us to open the group of patients who could benefit from this technology.
Before researchers prepare for large-scale clinical trials, they plan to incorporate additional imaging modes to detect other diseases
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