Friday, 14 December 2018

Cancer Nanotechnology


Nanotechnology is the manipulation of matter to be applied as materials, functionalized structures, devices, or systems (approximately the 1-100 nanometer range) at the atomic, molecular, or macromolecular scales with varied and new properties. It has great potential in almost, every sector, ranging from healthcare to construction and thus, is a rapidly outstretching area of research.
In the healthcare industry, the application of nanotechnology is termed as Nanomedicine, promising the revolution of medical application from the drug delivery to diagnosis and treatment and in many areas of Research and Development. The greatest advantage of nanomedicine is that the size of the nanomaterials is the same as that of the biomolecules and other biological structures and so can be useful for both in vivo and in vitro research and applications.


The branch of Nanotechnology concerned with the application of nanomaterials (for tumor imaging and drug delivery) and its approaches for the diagnosis and treatment of cancer is termed as Cancer Nanotechnology.
  • Drug Delivery
In cancer, uncontrolled abnormal cells grow rapidly and destroy the normal and healthy adjacent tissues and cells and often spread into other parts of the body via lymph and blood (Metastasis). Drugs and treatments associated with cancer often lead to various side effects but through nanotechnology, there have been possibilities of drug delivery and its action to specific tumor cells and on the healthy adjacent cells thus, lowering the overall drug consumption and side effects. Abraxane is one of the most popular nanotechnology-based drugs that are commercially available to treat Breast cancer and pancreatic cancer.
  • Imaging and Diagnosis
Nanotechnology-enabled imaging agents and cancer drugs enhance and improve the images produced by Ultrasound and MRI. Some of the examples of such nanoparticles include Quantum Dots in conjunction with MRI can produce great images of tumor sites. Cadmium Selenide, when injected into the body, seep into the tumors and glows when exposed to the Ultraviolet light thus, guides for the accurate site of the tumor.
  • Treatment and Therapy
Researches are going on Cancer Nanotechnology for creating the new therapeutics which is far beyond the drug delivery. The multiple types of biomolecules encapsulated nanoparticle in conjunction with ligands can be useful for therapeutic effect enabling combination drug delivery, multi-modality treatment and combined therapeutic and diagnostic, known as “theranostic,” action.

It can also be used for the development of research tools for the advanced study of cancer which may include in vitro tumor models and use nanoparticle probes to study cellular drug responses and mechanisms.

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